Supplements I Take, and Why: Turmeric

Turmeric/Curcumin

From Web MD

 http://www.webmd.com/vitamins-supplements/ingredientmono-662-turmeric.aspx?activeingredientid=662

Turmeric is a spice that comes from the turmeric plant. It is commonly used in Asian food. You probably know turmeric as the main spice in curry. It has a warm, bitter taste and is frequently used to flavor or color curry powders, mustards, butters, and cheeses. But the root of turmeric is also used widely to make medicine. It contains a yellow-colored chemical called curcumin, which is often used to color foods andcosmetics.

Turmeric is used for arthritis, heartburn (dyspepsia), joint pain, stomach pain, Crohn's disease and ulcerative colitis, bypass surgery, hemorrhage, diarrhea, intestinal gas, stomach bloating, loss of appetite, jaundice, liver problems, Helicobacter pylori (H. pylori) infection, stomach ulcers, irritable bowel syndrome (IBS), gallbladderdisorders, high cholesterol, a skin condition called lichen planus, skin inflammationfrom radiation treatment, and fatigue.

It is also used for headaches, bronchitis, colds, lung infections, fibromyalgia, leprosy, fever, menstrual problems, itchy skin, recovery after surgery, and cancers. Other uses include depression, Alzheimer's disease, swelling in the middle layer of the eye (anterior uveitis), diabetes, water retention, worms, an autoimmune disease called systemic lupus erythematosus (SLE), tuberculosis, urinary bladder inflammation, and kidney problems.

Some people apply turmeric to the skin for pain, ringworm, sprains and swellings, bruising, leech bites, eye infections, acne, inflammatory skin conditions and skin sores, soreness inside of the mouth, infected wounds, and gum disease.

Turmeric is also used as an enema for people with inflammatory bowel disease.

In food and manufacturing, the essential oil of turmeric is used in perfumes, and its resin is used as a flavor and color component in foods.

Don't confuse turmeric with Javanese turmeric root (Curcuma zedoaria).

How does it work?

Turmeric contains the chemical curcumin. Curcumin and other chemicals in turmeric might decrease swelling (inflammation). Because of this, turmeric might be beneficial for treating conditions that involve inflammation

TURMERIC USES & EFFECTIVENESS

Possibly Effective for:

• High cholesterol. Research suggests that taking turmeric extract by mouth twice daily for 3 months reduces total cholesterol, low-density lipoprotein (LDL or "bad") cholesterol, and triglycerides in overweight people with high cholesterol.
• Osteoarthritis. Some research shows that taking turmeric extracts, alone or in combination with other herbal ingredients, can reduce pain and improve function in people with osteoarthritis. In some research, turmeric worked about as well as ibuprofen for reducing osteoarthritis pain. However, it does not seem to work as well as diclofenac for improving pain and function in people with osteoarthritis.
• Itching (pruritus). Research suggests that taking turmeric by mouth three times daily for 8 weeks reduces itching in people with long-term kidney disease. Also, early research suggests that taking a specific combination product (C3 Complex, Sami Labs LTD) containing curcumin plus black pepper or long pepper daily for 4 weeks reduces itching severity and improves quality of life in people with chronic itching caused by mustard gas.

Possibly Ineffective for:

• Stomach ulcers. Some research suggests that taking turmeric three times daily for 8 weeks does not improve stomach ulcers. Also, taking powdered turmeric four times daily for 6 weeks seems to be less effective than taking a conventional antacid.

Insufficient Evidence for:

• Alzheimer's disease. Early research shows that taking curcumin, a chemical found in turmeric, daily for 6 months does not benefit people with Alzheimer's disease.
• Eye inflammation (anterior uveitis). Early research suggests that taking curcumin, a chemical found in turmeric, might improve symptoms of long-term inflammation in the middle layer of the eye.
• Colorectal cancer. Early research suggests that taking a specific turmeric product containing turmeric extract and Javanese turmeric extract (P54FP, Phytopharm plc., Godmanchester, United Kingdom) might stabilize some measures of colon cancer. There is also early evidence that taking curcumin, a chemical found in turmeric, daily for 30 days can reduce the number of precancerous glands in the colon of people at high risk of cancer.
• Bypass surgery (coronary artery bypass graft surgery). Early research suggests that taking curcuminoids, which are chemicals found in turmeric, starting 3 days before surgery and continuing for 5 days after surgery can lower the risk of a heart attack following bypass surgery.
• Skin wounds related to cancer. Early research suggests that applying a turmeric ointment might help to relieve odor and itching caused by wounds associated with different types of cancer.
• A type of inflammatory bowel disease called Crohn's disease. Some evidence suggests that taking curcumin, a chemical found in turmeric, daily for one month can reduce bowel movements, diarrhea, and stomach pain in people with Crohn's disease.
• Depression. Early research suggests that taking curcumin, a chemical found in turmeric, twice daily for 6 weeks is as effective as the antidepressant medication fluoxetine in people with depression.
• Diabetes. Early research suggests that taking turmeric extract twice daily for 9 months can reduce the number of people with prediabetes who develop diabetes.
• Stomach upset (dyspepsia). Some research shows that taking turmeric by mouth four times daily for 7 days might help improve an upset stomach.
• Gum disease (gingivitis). Early research suggests that using a turmeric mouthwash is as effective as a drug-therapy mouthwash for reducing gum disease and bacteria levels in the mouth of people with gingivitis.
• Stomach ulcers caused by Helicobacter pylori (H pylori) infection. Early research suggests that taking turmeric daily for 4 weeks is less effective than conventional treatment for eliminating certain bacteria (H. pylori) that can cause stomach ulcers.
• Irritable bowel syndrome (IBS). Early research suggests that taking a turmeric extract (Cynara Turmeric, Lchtwer Pharma) daily for 8 weeks reduces the occurrence of IBS in people with IBS who are otherwise healthy.
• Joint pain. Research shows that taking a specific combination product (Instaflex Joint Support, Direct Digital, Charlotte, NC) containing turmeric and other ingredients three times daily for 8 weeks reduces the severity of joint pain. But it does not appear to help joint stiffness or improve joint function.
• Skin rash (Lichen planus). Taking a certain product (Curcumin C3 Complex, Sabinsa Corp) containing chemicals found in turmeric three times daily for 12 days can reduce skin irritation caused by lichen planus.
• Prostate cancer. Research suggests that taking a formula containing broccoli powder, turmeric powder, pomegranate whole fruit powder, and green tea extract three times daily for 6 months prevents an increase in prostate specific antigen (PSA) levels in men with prostate cancer. PSA levels are measured to monitor how well prostate cancer treatment is working. However, it's not yet known if this formula reduces the risk of prostate cancer progression or recurrence.
• Inflammation in the mouth and/or esophagus from radiation treatment. Early research suggests that swishing a turmeric solution in the mouth six times daily for 6 weeks reduces the risk of inflammation in the mouth and/or esophagus caused by radiation treatment in people with head and neck cancer.
• Rheumatoid arthritis (RA). Early research suggests that curcumin, a chemical found in turmeric, might reduce some RA symptoms, including morning stiffness, walking time, and joint swelling. Other research shows that taking a turmeric product (BCM-95, Arjuna Natural Extracts, India) twice daily reduces RA symptoms more than conventional medication.
• Recover from surgery. Early research suggests that taking curcumin, a chemical found in turmeric, daily for up to one week after surgery can reduce pain, fatigue, and the need for pain medications.
• An inflammatory disease called systemic lupus erythematosus (SLE). Early research suggests that taking turmeric by mouth three times daily for 3 months can reduce blood pressure and improve kidney function in people with kidney inflammation (lupus nephritis) caused by systemic lupus erythematosus.
• Tuberculosis. Early research suggests that taking a product containing turmeric and Tinospora cordifolia can reduce bacteria levels, improve wound healing, and reduce liver toxicity caused by antituberculosis therapy in people with tuberculosis who are receiving antituberculosis therapy.
• A type of inflammatory bowel disease called ulcerative colitis. Some early research suggests that taking curcumin, a chemical found in turmeric, daily for up to 6 months can reduce symptoms and the recurrence of ulcerative colitis when used in combination with conventional treatments. Other research shows that taking turmeric extract as an enema might help people with this condition.
• Acne.
• Jaundice.
• Hepatitis.
• Diarrhea.
• Fibromyalgia.
• Liver and gallbladder problems.
• Headache.
• Menstrual problems.
• Pain.
• Ringworm.
• Bruising.
• Other conditions.

More evidence is needed to rate turmeric for these uses.

TURMERIC SIDE EFFECTS & SAFETY

Turmeric is LIKELY SAFE when taken by mouth or applied to the skin appropriately for up to 8 months.

Turmeric is POSSIBLY SAFE when it is used as an enema or a mouthwash in the short-term.

Turmeric usually does not cause significant side effects; however, some people can experience stomach upset, nausea, dizziness, or diarrhea.

In one report, a person who took very high amounts of turmeric, over 1500 mg twice daily, experienced a dangerous abnormal heart rhythm. However, it is unclear if turmeric was the actual cause of this side effect. Until more is known, avoid taking excessively large doses of turmeric.

Special Precautions & Warnings:

Pregnancy and breast-feeding: During pregnancy and while breast-feeding, turmeric is LIKELY SAFE when taken by mouth in amounts commonly found in food. However, turmeric is LIKELY UNSAFE when taken by mouth in medicinal amounts during pregnancy. It might promote a menstrual period or stimulate the uterus, putting the pregnancy at risk. Do not take medicinal amounts of turmeric if you are pregnant. There is not enough information to rate the safety of medicinal amounts of turmeric during breast-feeding. It is best not to use it.

Gallbladder problems: Turmeric can make gallbladder problems worse. Do not use turmeric if you have gallstones or a bile duct obstruction. 

Bleeding problems: Taking turmeric might slow blood clotting. This might increase the risk of bruising and bleeding in people with bleeding disorders. 

Diabetes: Curcumin, a chemical in turmeric, might decrease blood sugar in people with diabetes. Use with caution in people with diabetes as it might make blood sugar too low. 

A stomach disorder called gastroesophageal reflux disease (GERD): Turmeric can cause stomach upset in some people. It might make stomach problems such as GERD worse. Do not take turmeric if it worsens symptoms of GERD. 

Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Turmeric contains a chemical called curcumin, which might act like the hormone estrogen. In theory, turmeric might make hormone-sensitive conditions worse. However, some research shows that turmeric reduces the effects of estrogen in some hormone-sensitive cancer cells. Therefore, turmeric might have beneficial effects on hormone-sensitive conditions. Until more is known, use cautiously if you have a condition that might be made worse by exposure to hormones. 

Infertility: Turmeric might lower testosterone levels and decrease sperm movement when taken by mouth by men. This might reduce fertility. Turmeric should be used cautiously by people trying to have a baby. 

Iron deficiency: Taking high amounts of turmeric might prevent the absorption of iron. Turmeric should be used with caution in people with iron deficiency. 

Surgery: Turmeric might slow blood clotting. It might cause extra bleeding during and after surgery. Stop using turmeric at least 2 weeks before a scheduled surgery.

TURMERIC INTERACTIONS

Moderate Interaction Be cautious with this combination

• Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with TURMERIC
  
  Turmeric might slow blood clotting. Taking turmeric along with medications that also slow clotting might increase the chances of bruising and bleeding.
  
  Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

TURMERIC DOSING

BY MOUTH:

• For high cholesterol: 1.4 grams of turmeric extract in two divided doses daily for 3 months has been used.
• For itching (pruritus): 1500 mg of turmeric in three divided doses daily for 8 weeks has been used. Also, a specific product containing turmeric extract (C3 Complex, Sami Labs LTD) plus black pepper or long pepper has been used daily for 4 weeks.
• For osteoarthritis: 500 mg of a non-commercial turmeric product four times daily for 4-6 weeks has been used. 500 mg of a specific turmeric extract (Turmacin, Natural Remedies Pvt. Ltd.) has been used twice daily for 6 weeks (89721). 500 mg of a specific turmeric extract (Meriva, Indena) containing turmeric and phosphatidylcholine has been used twice daily for 2-3 months. Other combination products have also been used

Meals for Two

Vegetarian - Mushroom

Mushroom Burger

1 very large Portobello mushroom cap
1 veggie burger patty
1 T olive oil
2 T organic spaghetti sauce
1 slice mozzarella cheese
1 T sofrito

Remove stem from mushroom.  Dice stem.  With top of cap down on pan, gently fry cap and stem pieces over medium-low heat in 1 T oil, covered, for 15 minutes, or until liquid is released.  Save liquid to add to mushroom soup.

Heat another skillet to very hot with 1 T oil.  Remove veggie burger from freezer and put in pan.  Cover and reduce heat to medium.  Cook 4 to 6 minutes on each side.  Turn off heat.

Place cooked mushroom on baking pan.  Add burger.  Cover with sauce, then cheese.  Bake in toaster oven on 'bake' setting at 400 degrees just until cheese is melted (about 10 to 20 minutes).  Garnish with sofrito.

Stuffed Mushroom

2 medium Portobello mushroom caps
1/4 C prepared rice
2 T pizza sauce or 2 large slices tomato

Remove stems from mushrooms.  Dice stems.  With tops of caps down on pan, gently fry caps and stem pieces over medium-low heat in 1 T oil, covered, for 15 minutes, or until liquid is released.  Save liquid to add to mushroom soup.

Place cooked mushrooms on baking pan.  Add as much rice as can be held by caps.  Cover with pizza sauce or slice of tomato.  Bake in toaster oven on 'bake' setting at 400 degrees about 10 minutes.